(no subject)

Alzheimer’s risk may grow with higher use. For instance, it found people taking a minimum of 25 mg of an anticholinergic called diphenhydramine (or one Advil PM, Tylenol PM, Motrin PM, or Benadryl pill) a day for three to 12 months increased their relative risk for dementia by 19 percent; one to three years, 23 percent; three to seven years, 54 percent compared to no use (if the statistically significant increase occurred among the latter group).

Furthermore, this was the first study to find that dementias associated with anticholinergics may not be reversible even years after drug use stops.
http://www.dddmag.com/articles/2015/04/strong-link-found-between-dementia-common-anticholinergic-drugs

(no subject)

71 drugs approved by the FDA from 2002 to 2014 for solid tumours have resulted in median gains in progression-free and overall survival of only 2.5 and 2.1 months, respectively,” he said, “also, only 42 percent met the American Society of Clinical Oncology Cancer Research Committee’s criteria for meaningful results for patients.”

http://www.dddmag.com/news/2015/05/cancer-drugs-approved-quickly-not-patients-benefit

(no subject)

The use of glycated haemoglobin (sugar-bound haemoglobin, or HbA1c) is now used by most doctors to assist in the diagnosis of type 2 diabetes. However new research published in Diabetologia (the journal of the European Association for the Study of Diabetes) highlights how anaemia—a common condition in the general population, especially in women—can lead to a false diagnosis of diabetes based on HbA1c, when a person’s blood sugar control is actually normal.
http://www.dddmag.com/news/2015/05/anemia-distorts-regular-method-diabetes-diagnosis